- What is the cost-effectiveness for specialist clothing compared to normal care of children with moderate to severe eczema?
Lead Investigator: Dr Kim Thomas, Nottingham
Intervention: Use of specialist clothing such as Dermasilk® and Comfifast® and compare with normal treatment over six months.
Status: Approved for development , working on the protocol. If you are interested in this study and would like more information please contact Dr Kim Thomas.
- Psychological therapies for the treatment of patients with alopecia
| Lead investigator: | Nigel Hunt |
| Interventions: | Psychological therapies delivered by Graduate Mental Health Workers. |
| Outcomes: | To be decided |
| Justification for the trial: |
There are currently no RCTs assessing the usefulness of such therapies in the treatment of alopecia. |
If you would like further details about this study idea, or would like to get involved please contact Kim Thomas.
- Mohs’ surgery versus single complete excision in the management of cutaneous squamous cell carcinoma
Lead investigator: None identified Interventions: Mohs’ surgery or single complete excision Outcomes: Primary outcome measure is disease free survival at 5 years. Justification for the trial: There are no prospective or comparative studies of Mohs’ surgery versus attempted single complete excision of SCC.
If you would like further details about this study idea, or would like to get involved, please contact Kim Thomas.
Please note this study cannot be progressed through the Network until a Lead Investigator has been identified.
- A randomised controlled study of Mohs’ versus excisional surgery for the management of peri-ocular basal cell carcinoma.
Lead investigator: Colin Fleming, Ninewells Hospital and Medical School, Dundee Interventions: Outcomes: To be decided Status: We are awaiting the outcome of a Cochrane sytematic review before this study is progressed.
If you would like further details about this study idea, or would like to get involved, please contact Kim Thomas.
Please note that this study cannot be progressed through the Network until the outcome of a Cochrane systematic review on the subject is known.
- Is spironolactone effective in the treatment of female pattern hair loss?
Lead investigator: Dr Andrew Messenger, Sheffield. Interventions: Oral spironolactone + topical vehicle vs oral placebo + topical minoxidil. Outcomes: Hair density - terminal hairs/unit area and global photographic assessment. Justification for the trial: Antiandrogens are widely used to treat this condition but no good RCT evidence of efficacy.
Status: Initial approval from Trial Generation & Prioritisation Panel. To be presented to UKDCTN Steering Committee in 2010. For further information about this research idea please contact Margaret McPhee.
- Treatment for Delusional Parasitosis
Lead investigator: Peter Lepping, Consultant Psychiatrist, Wrexham Interventions: Comparing antipsychotic drugs Outcomes: To be decided Justification for the trial: There are currently no RCTs evaluating the treatment of delusional parasitosis
A pilot study is taking place in London. If you would like further details about this study, or would like to get involved, please contact Margaret McPhee.
