| Study | Description | Results, publications and further work |
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TREAT (Eczema) Study
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RCT looking at the efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people |
Results published in BJD
Video explaining results
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THESEUS
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Observational study into the management of Hidradenitis Suppurativa
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Results published in BJD |
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ALPHA (Hand Eczema) Study
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Comparing Alitretinoin and Puva for chronic hand eczema. |
Waiting publication |
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SAFA (Female acne) Study
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RCT looking at the effectiveness of spironolactone for acne by comparing two treatment groups: either spironolactone or placebo (dummy pill).
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Results published in BMJ
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HEALS Feasibility Study
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Cohort study looking at compression healing after excisional surgery for skin cancer on the lower leg.
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Results published in CED Part 1
Results published in CED Part 2
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Surgical site infection in ulcerated skin cancers (OASIS study)
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An observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (feasibility study)
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Results published in CED
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Best Emollients for Eczema (BEE Study)
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A study comparing different emollients - lotion, cream, gel and ointment in children with eczema
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Results published in The Lancet
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Trial of Eczema Allergy Screening Tests (TEST Study)
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What is the value of food allergy testing in infants with early onset eczema? (feasibility study)
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Results published in CED
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Anakinra for palmoplantar pustula psoriasis (APRICOT Study)
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Treatment of Pustular Psoriasis with IL-1 receptor antagonist anakinra
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Results published in BJD
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Barrier Enhancement for Eczema Prevention (BEEP Study)
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The use of emollients for newborn babies to prevent eczema
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Results published in The Lancet
Five year results 2022
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HI-Light Vitiligo Trial
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Randomised controlled trial of topical corticosteroid and home‐based narrowband UVB for active and limited vitiligo
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Results published in BJD
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Clothing for the relief of Eczema Symptoms (CLOTHES) study
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A study designed to evaluate the role of specialist clothing eczema management.
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Results in PubMed
PLOS Medicine article April 2017
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The Bullous Pemphigoid Steroids and Tetracyclines (BLISTER) study
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Examined whether doxycycline would be a good alternative to prednisolone for treating bullous pemphigoid.
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Results in The Lancet
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Systemic Therapy for Vulval Erosive Lichen Planus (hELP) trial
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A study that evaluated the effectiveness of tablet treatments for moderate or severe vulval erosive lichen planus.
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Results in PubMed
Lessons learned from the hELP study
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Study of Treatments for Pyoderma Gangrenosum Patients (STOP GAP) trial
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A study that compared the use of prednisolone and ciclosporin for the treatment of pyoderma gangrenosum.
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Results in PubMed
BMJ article June 2015
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Skin cancer prevention (SCC) in organ transplant patients (SPOT Study)
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Treatments for preventing squamous cell carcinoma in organ transplant patients using topical treatments (feasibility)
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Results published in CED
Patient preferences article published in PubMed
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Surgery vs imiquimod for nodular and superficial basal cell carcinoma (SINS) trial
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The SINS trial compared excisional surgery with imiquimod cream for nodular and superficial basal cell carcinoma.
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Results in The Lancet Oncology
Year 3 data 2013
Results in PubMed
Year 5 data 2015
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Softened Water Eczema Trial (SWET) study
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A study that evaluated whether using an ion-exchange water softener could help reduce eczema severity
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Results in PubMed
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Effect of topical imiquimod on lentigo maligna (LIMIT-1) trial
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The LIMIT-1 trial was designed to determine whether imiquimod is a sufficiently effective treatment for lentigo maligna
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Results in PubMed
BJD article October 2016
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Pilot HI-LIGHT Vitiligo Trial
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Pilot trial of light therapy for the treatment of vitiligo at home
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Results in PubMed
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Prophylactic Antibiotics for the Treatment of Cellulitis at Home (PATCH) I & II trials
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Randomised controlled trial to investigate whether prophylactic antibiotics (taken for 12 & 6 months) can prevent further episodes of cellulitis of the leg
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PATCH I Results
PATCH II Results
Economic Analysis Feb 2014
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